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Qué (quién) es ODC internal ribosome entry site (IRES) - definición
Internal ribosome entry site
![[[Poliovirus]] genome, including an IRES.](https://commons.wikimedia.org/wiki/Special:FilePath/Poliovirus genome.png?width=200 "[[Poliovirus]] genome, including an IRES.")
SEQUENCE IN THE 5′ UTR OF SOME MRNAS WHERE A RIBOSOME CAN BIND
Internal Ribosome Entry Sites
An internal ribosome entry site, abbreviated IRES, is an RNA element that allows for translation initiation in a cap-independent manner, as part of the greater process of protein synthesis. In eukaryotic translation, initiation typically occurs at the 5' end of mRNA molecules, since 5' cap recognition is required for the assembly of the initiation complex.
ODC internal ribosome entry site (IRES)
In molecular biology, the ODC internal ribosome entry site (IRES) is an RNA element present in the 5′ UTR of the mRNA encoding ornithine decarboxylase. It has been suggested that this IRES allows cap-independent translation of ornithine decarboxylase at the G2/M phase of the cell cycle, however there is some doubt about this.
Ribosome-binding site
A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible for the recruitment of a ribosome during the initiation of translation. Mostly, RBS refers to bacterial sequences, although internal ribosome entry sites (IRES) have been described in mRNAs of eukaryotic cells or viruses that infect eukaryotes.
Wikipedia
ODC internal ribosome entry site (IRES)
In molecular biology, the ODC internal ribosome entry site (IRES) is an RNA element present in the 5′ UTR of the mRNA encoding ornithine decarboxylase. It has been suggested that this IRES allows cap-independent translation of ornithine decarboxylase at the G2/M phase of the cell cycle, however there is some doubt about this.
